FAANG List Archived Post

From david.machugh@ucd.ie  Thu May  5 08:28:49 2016
From: "David MacHugh" <david.machugh@ucd.ie>
Subject: PhD position available in UCD,Dublin Ireland: Functional
       genomics of the host response to Mycobacterium bovis infection
Date: Thu, 5 May 2016 11:56:32 +0100
To: Multiple Recipients of FAANG <faang@animalgenome.org>

A four-year PhD studentship in infection biology and functional genomics of
bovine tuberculosis is available at the Animal Genomics Laboratory, University
College Dublin.

Applicants should have a 2.1 honours degree or higher in Immunology,
Genetics/Genomics, Microbiology, Cell Biology, Biochemistry, Animal Science,
Veterinary Medicine or a cognate discipline.

PDF poster advert: http://bit.ly/PhDStudentship

PhD Project Title

Functional genomics of the host response to Mycobacterium bovis infection:
development of next-generation control tools for bovine tuberculosis

Project Description

Tuberculosis is a devastating disease of humans and animals. Mycobacterium
bovis, which cause bovine tuberculosis, is a major zoonotic pathogen and
causes losses to global agriculture of approx. 2.7 billion per annum. To
develop strategies to control bovine tuberculosis, we need to understand how
the pathogen causes disease and how this impacts host immunobiology and
physiology.

This thematic structured PhD research project will focus on peripheral blood-
based functional genomics of mRNA and microRNA transcriptomes to develop
infection biosignatures of tuberculosis in domestic cattle. An integrative
genomics approach will be used, encompassing gene expression information from
in vitro macrophage infection challenge experiments, experimental animal
infection models and validation studies of field-infected cattle. In
addition, the research project will be carried out within a One Health
framework, leveraging information from parallel genomics studies of host-
pathogen interactions in human tuberculosis caused by Mycobacterium
tuberculosis.

Background

University College Dublin is the largest University in Ireland whose origin
dates back to 1854. There are more than 26,000 students, including over 6,000
international students, on the main UCD Belfield campus. The successful
applicant will join a large group of researchers investigating bovine and
human tuberculosis, and will have access to outstanding research facilities
at the UCD Animal Genomics Laboratory and at the UCD Conway Institute of
Biomolecular and Biomedical Research. The student will be co-supervised by
Prof David MacHugh (http://goo.gl/CvWZ7G) and Prof Stephen Gordon
(http://goo.gl/Gpgh7f) and will be enrolled in the UCD Thematic PhD Programme
in Infection Biology (http://www.ucd.ie/infectbio ), which includes
advancedtraining in immunobiology, functional genomics, population genomics,
integrative genomics, computational biology and bioinformatics.

Scholarship details

Four-year Science Foundation Ireland (SFI) funded position, 18,000 stipend
per annum, postgraduate fees funded separately by the project.

Unfortunately, due to funding restrictions, this position is available to EU
residents (eligible for EU postgraduate fees) only. Applications from nonEU
residents will not be shortlisted.

Closing Date for applications:
Close of business, Friday 17th June 2016

Email applications (CV and contact details for at least two scientific
referees) to: animal.genomics.ucdgmail.com
Start date: 2016/2017 academic year

Enquiries
Prof David MacHugh
Phone: +353-1-716-6256
Email: animal.genomics.ucdgmail.com